Searching for a Neurobiological Basis for Self-Medication Theory in ADHD Comorbid With Substance Use Disorders

Abstract

The ADHD + SUD group had lower striatal DAT density in comparison with ADHD without SUD. It is possible to speculate that the use of cannabis and cocaine is responsible for the lower striatal DAT density in this group which would help in understanding the neurobiological basis for the self-medication theory in ADHD adolescents.