Diseases of the Colon & Rectum · 2002 · 123 citations · 14 references
MedicineAnesthesiologySurgeryAnesthesiaLocal AnesthesiaPain ManagementAnalgesiaInjection TechniquesLocal Anesthesia For Pain ControlOpioid AnalgesicsPostoperative PainAnesthetic Efficacy AssessmentHemorrhoidal BleedingLocal Anesthetic InfiltrationLocal Infiltration AnalgesiaPain Management After SurgeryPain ScoresPatient ComfortRopivacaine Use
PURPOSE: This study was conducted to assess the efficacy of infiltration with a new local anesthetic (ropivacaine) to control pain after hemorrhoidal surgery. METHODS: Thirty-four patients who underwent hemorrhoidectomy were included in a double-blind, randomized study to assess the analgesic effect of a perianal infiltration with 40 ml of 0.75 percent ropivacaine compared with isotonic saline infiltration. Postoperatively, pain was assessed on a visual analog scale, and intravenous morphine consumption was measured with patient-controlled administration. RESULTS: In the ropivacaine group, patients had lower visual analog scale scores at 1, 3, and 6 hours after infiltration and required fewer cumulative doses of morphine (patient-controlled administration) at 3, 6, and 12 hours. Side effects were comparable in the two groups. CONCLUSION: Local infiltration with ropivacaine improves pain control and patient comfort in the immediate postoperative course of hemorrhoidal surgery.
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Acute Toxicity of Ropivacaine Compared with That of Bupivacaine
D.B. SCOTT, Alistair Lee, D. Fagan et al. · Anesthesia & Analgesia · 1989 · 772 citations