Concepedia

Impact of Successful Treatment of Acromegaly on Overnight Heart Rate Variability and Sleep Apnea

D. S. Chemla, Pierre Attal, Luigi Maione, A.S. Veyer, Ghassan Mroue, Dany Baud, Sylvie Salenave, Peter Kamenický, S Bobin, Philippe Chanson

The Journal of Clinical Endocrinology & Metabolism · 2014 · 58 citations · 35 references

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Abstract

Early after successful treatment of acromegaly, we observed increased parasympathetic modulation/decreased sympathetic modulation of the nighttime heart rate, an effect that seems unrelated to changes in sleep apnea status. Treatments aimed at normalizing IGF-1 may improve cardiovascular homeostasis through improved cardiac autonomic nervous system modulation.

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