Sex differences in the rapid and the sustained antidepressant-like effects of ketamine in stress-naïve and “depressed” mice exposed to chronic mild stress

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Nanxin Li, Boyoung Lee, Rongjian Liu et al. · Science · 2010 · 2.9K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Grand challenges in global mental health

Pamela Y. Collins, Vikram Patel, Sarah S. Joestl et al. · Nature · 2011 · 2.1K citations · Full text

Public Health, Health Policy, Psychiatry +12

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

Anita E. Autry, Megumi Adachi, E. D. Nosyreva et al. · Nature · 2011 · 1.9K citations

Medicine, Neuroscience, Pharmacology +9

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

Sungho Maeng, Carlos A. Zarate, Jing Du et al. · Biological Psychiatry · 2007 · 1.1K citations

Medicine, Neuroscience, Pharmacology +16

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

Nanxin Li, Rong-Jian Liu, Jason M. Dwyer et al. · Biological Psychiatry · 2011 · 1.1K citations

Medicine, Neuroscience, Pharmacology +17