Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Roger Stupp, Warren Mason, Martin J. van den Bent et al. · New England Journal of Medicine · 2005 · 21.6K citations · Full text

Medicine, Oncology, Radiation Oncology +12

Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas

Henry Brem, Steven Piantadosi, P. C. Burger et al. · The Lancet · 1995 · 1.4K citations · Full text

Pharmacy, Oncology, Surgery +16

A phase 3 trial of local chemotherapy with biodegradable carmustine(BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma

Manfred Westphal, Dana Hilt, Enoch Bortey et al. · Neuro-Oncology · 2003 · 1.3K citations · Full text

Medicine, Oncology, Surgery +17

Interstitial Chemotherapy with Carmustine-loaded Polymers for High-grade Gliomas: A Randomized Double-blind Study

S. Valtonen, UI la Timonen, Petri Toivanen et al. · Neurosurgery · 1997 · 427 citations

Medicine, Neurosurgery, Oncology +15

Gliadel® wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial

Manfred Westphal, Zvi Ram, V. Riddle et al. · Acta Neurochirurgica · 2006 · 418 citations

Medicine, Neurosurgery, Surgery +9