A phase I study of irinotecan and infusional cisplatin for advanced non-small-cell lung cancer

CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer.

N Masuda, M. Fukuoka, Y Kusunoki et al. · Journal of Clinical Oncology · 1992 · 452 citations

Medicine, Oncology, Pharmacology +8

Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors.

Takehiko Kunimoto, Kazuo Nitta, Takashi Tanaka et al. · PubMed · 1987 · 412 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. CPT-11 Gastrointestinal Cancer Study Group.

Y. Shimada, Makoto Yoshino, A Wakui et al. · Journal of Clinical Oncology · 1993 · 396 citations

Medicine, Oncology, Pharmacology +15

Phase I and pharmacokinetic trial of weekly CPT-11.

Mace L. Rothenberg, John G. Kuhn, Howard A. Burris et al. · Journal of Clinical Oncology · 1993 · 303 citations

Medicine, Oncology, Pharmacology +16

Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin

Lung Cancer · 1992 · 238 citations

Medicine, Cancer Biology, Oncology +7