COMPARISON OF SPECTRAL-DOMAIN AND TIME-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IN THE DETECTION OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION ACTIVITY

Abstract

In this neovascular age-related macular degeneration patient population, spectral-domain ocular coherence tomography was a superior diagnostic tool when compared with TD-OCT, with each spectral domain platform and acquisition setting identifying significantly more exudative disease activity. The two spectral domain platforms (Cirrus and Spectralis) were not directly compared because identical image acquisition parameters were not used. No individual imaging modality demonstrated a diagnostic advantage for detecting subretinal fluid versus intraretinal cysts.