Concepedia

Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPα secretion by deprenyl

Hongqi Yang, Maowen Ba, Ru‐Jing Ren, Yuhong Zhang, Jianfang Ma, Jing Pan, Guoqiang Lü, Shengdi Chen

Neurochemistry International · 2006 · 22 citations · 38 references

DOI

Concepts

References

38

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Azad Bonni, Anne Brunet, Anne E. West et al. · Science · 1999 · 1.9K citations

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Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

Sven Lammich, Elżbieta Kojro, Rolf Postina et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

, , +17

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

Mark P. Mattson, Bin Cheng, Alan R. Culwell et al. · Neuron · 1993 · 799 citations

, , +16

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

Steven L. Roberds · Human Molecular Genetics · 2001 · 703 citations

, , +17

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model

Rolf Postina, Anja Schroeder, Ilse Dewachter et al. · Journal of Clinical Investigation · 2004 · 621 citations

, , +17