ASSISTED REPRODUCTION TECHNOLOGY FOR PATIENTS WITH CONGENITAL BILATERAL ABSENCE OF VAS DEFERENS

Hiroshi Okada, Kunihiko Yoshimura, Hitoshi Fujioka, Noboru Tatsumi, Akinobu Gotoh, Masato Fujisawa, Kazuo Gohji, Soichi Arakawa, Hiroshi Kato, Shinichiro Kobayashi,

The Journal of Urology · 1999 · 29 citations · 28 references

Abstract

The 5T variant in intron 8 polythymidine tract was identified with high allelic frequency in Japanese patients with congenital bilateral absence of the vas deferens, suggesting that the disease in Japan is also partially caused by this particular mutation of the cystic fibrosis transmembrane conductance regulator gene. Modern assisted reproduction technology offers an important option for patients with congenital bilateral absence of the vas deferens.

References

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