Myocardial Infarct Size-Limiting and Anti-Arrhythmic Effects of Mildronate Orotate in the Rat Heart

The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusion

Michael Walker, Michael J. Curtis, David J. Hearse et al. · Cardiovascular Research · 1988 · 1.1K citations

Medicine, Cardiology, Clinical Cardiology +13

A Randomized Clinical Trial of Trimetazidine, a Partial Free Fatty Acid Oxidation Inhibitor, in Patients With Heart Failure

Gabriele Fragasso, Altin Palloshi, Patrizia Puccetti et al. · Journal of the American College of Cardiology · 2006 · 268 citations

Medicine, Pharmacology, Pharmacotherapy +13

3-(2,2,2-Trimethylhydrazinium)propionate(thp)-a novel γ-butyrobetaine hydroxylase inhibitor with cardioprotective properties

Boris Z. Simkhovich, Zhanna V. Shutenko, Dainuvīte V. Meirēna et al. · Biochemical Pharmacology · 1988 · 110 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

Mildronate, an Inhibitor of Carnitine Biosynthesis, Induces an Increase in Gamma-Butyrobetaine Contents and Cardioprotection in Isolated Rat Heart Infarction

Edgars Liepinsh, Reinis Vilšķe̅rsts, Dagnija Loča et al. · Journal of Cardiovascular Pharmacology · 2006 · 77 citations

Medicine, Biochemistry, Pharmacology +10

Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart

Edgars Liepinsh, Reinis Vilšķe̅rsts, Elina Skapare et al. · Life Sciences · 2008 · 69 citations

Life Sciences, Biochemistry, Physiology +13