Chemical Communications · 2010 · 161 citations · 26 references
EngineeringBioelectrochemistryDna AnalysisChemistryGold NanoparticlesBioanalysisAnalytical ChemistryAnalytical BiotechnologyNanosensorChemical SensorBiochemistryAmplified DetectionElectrochemistryBiomolecular EngineeringNovel Amplification StrategyNatural SciencesElectrochemical SensorElectroanalytical SensorPb2+ Ions
A novel amplification strategy based on DNAzyme functionalized gold nanoparticles was employed to enhance the sensitivity of an electrochemical sensor for detection of Pb2+. The detection limit is 0.028 nM, which is much lower than for other electrochemical DNAzyme sensors.
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