A Practical Real-Time Fourier Transform Infrared Detector for Liquid Chromatography

Abstract

A practical Fourier transform infrared system for real-time liquid chromatographic detection is described. Simple flowcell detection with automatic solvent subtraction is used, and detection of 500 ng of injected paraffin oil is demonstrated. Results from several chromatographic runs illustrate the system capability to serve as a real time infrared detector and simultaneously acquire infrared spectra.