American Journal of Nephrology · 1991 · 55 citations · 0 references
MedicineInfectious DiseasesNephrologyInfectious Disease PathologyRenal PathologyRenal PathophysiologyAcute Kidney InjuryImmune-mediated Renal DiseaseInterstitial NephritisRenal DiseaseRenal ImmunopathologyRenal InflammationLeishmaniasis PathogenesisLeishmaniasis PathologyParasitic Renal DiseaseRenal Biopsy DiagnosisRenal Biopsy FindingsRenal Complement InjuryRenal DisordersVisceral Leishmaniasis
We describe the case of a 33-year-old male patient with an acute visceral leishmaniasis (Leishmania donovani) associated with an acute renal failure. The clinical manifestations were dominated by fever, oliguric renal failure and hepatic alterations. Serum C3 and C4 fractions of complement were decreased, and a renal biopsy demonstrated an interstitial nephritis with no glomerular involvement. The clinical course was favorable with recuperation of renal function without sequels.