Combining Fluorescent Probes and Biofunctional Magnetic Nanoparticles for Rapid Detection of Bacteria in Human Blood

Jinhao Gao, L. Li, Pak‐Leung Ho, Gannon C.K. Mak, Hongwei Gu, Bing Xu

Advanced Materials · 2006 · 175 citations · 25 references

Concepts

Abstract

Detection of bacteria in human blood within two hours is achieved through the use of vancomycin-functionalized FePt nanoparticles in combination with a vancomycin-conjugated fluorescent probe, as shown in the figure (B: bacteria; Van: vancomycin; FLA: fluorescein amine). This promises to be a sensitive and rapid protocol for detecting bacteria in blood products or other targets in biological samples.

References

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