The Journal of Clinical Endocrinology & Metabolism · 1972 · 39 citations · 0 references
Life SciencesEndocrinologyPhysiologyPhysiological Systems ModelingReproductive EndocrinologyReproductive PhysiologyEndocrine PhysiologyEndocrine Regulation Of ReproductionEndocrine System ModelingHormonal Regulation Of ReproductionMenstrual CycleOvarian PhysiologyEndocrine SimulationHormone Secretion DynamicsMenstrual Cycle DynamicsMenstrual Cycle EndocrinologyMenstrual Cycle Hormone DynamicsMenstrual Cycle RegulationModel Performance AnalysisModel Performance Evaluation
Performance of a mathematical model of the human menstrual cycle is described. Hypotheses regarding control of the cycle are developed and demonstrated by simulation. From model performance and mathematical principles it is suggested that this endocrine system is regulated by small, rapid hormone level changes. These signals may provide information characterizing the morphological state of the system on a moment to moment basis.