Concepedia

Antiestrogenic Regulation of Transforming Growth Factor Beta Receptors I and II in Human Breast Cancer Cells

Meredith Buck, J. VON DER FECHT, Cornelius Knabbe

Annals of the New York Academy of Sciences · 2002 · 14 citations · 5 references

DOI

Concepts

Abstract

To obtain more information about the interactions between antiestrogens and transforming growth factor beta (TGF-beta) signaling, we analyzed the influence of different types of antiestrogens on the expression of TGF-beta receptors I (TbetaRI) and II (TbetaRII). Our results show that antiestrogens selectively induce TbetaRII but not TbetaRI mRNA.

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