Upregulation of IGF-I in the goldfish retinal ganglion cells during the early stage of optic nerve regeneration

The Mitogenic and Myogenic Actions of Insulin-like Growth Factors Utilize Distinct Signaling Pathways

Sharon A. Coolican, Derina S. Samuel, Daina Z. Ewton et al. · Journal of Biological Chemistry · 1997 · 649 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

Hirohito Yamaguchi, Hong‐Gang Wang · Oncogene · 2001 · 400 citations

Life Sciences, Cell Biology, Molecular Biology +16

Insulin Rescues Retinal Neurons from Apoptosis by a Phosphatidylinositol 3-Kinase/Akt-mediated Mechanism That Reduces the Activation of Caspase-3

Alistair J. Barber, Makoto Nakamura, E Wolpert et al. · Journal of Biological Chemistry · 2001 · 288 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

Counteracting the Nogo Receptor Enhances Optic Nerve Regeneration If Retinal Ganglion Cells Are in an Active Growth State

Dietmar Fischer, Zhigang He, Larry I. Benowitz · Journal of Neuroscience · 2004 · 275 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Insulin-Like Growth Factor-I Protects Axotomized Rat Retinal Ganglion Cells from Secondary Death via PI3-K-Dependent Akt Phosphorylation and Inhibition of Caspase-3<i>In Vivo</i>

Pawel Kermer, Nikolaj Klöcker, Monika Labes et al. · Journal of Neuroscience · 2000 · 265 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17