Reversal of morphine, methadone and heroin induced effects in mice by naloxone methiodide

Mechanisms of fatal opioid overdose

Jason M. White, Rodney J. Irvine · Addiction · 1999 · 626 citations

Medicine, Neuroscience, Pharmacology +16

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

J. Bl�sig, A. Herz, Kimberly Reinhold et al. · Psychopharmacology · 1973 · 530 citations

Medicine, Pharmacokinetics, Pharmacology +14

The d- and l- isomers of methadone bind to the non-competitive site on the N-methyl-d-aspartate (NMDA) receptor in rat forebrain and spinal cord

Amy Gorman, Kathryn Elliott, Charles E. Inturrisi · Neuroscience Letters · 1997 · 394 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Methylnaltrexone for Reversal of Constipation Due to Chronic Methadone Use

Chun‐Su Yuan, Joseph Foss, Michael O’Connor et al. · JAMA · 2000 · 298 citations

Nursing, Pharmacology, Pharmacotherapy +17

Antagonism of gut, but not central effects of morphine with quaternary narcotic antagonists

James R. Russell, Paul Bass, Leon I. Goldberg et al. · European Journal of Pharmacology · 1982 · 226 citations

Medicine, Pharmacology, Pharmacotherapy +10