Astatine-211 labeling of protein using TCP as a bi-functional linker: synthesis and preliminary evaluation in vivo and in vitro

Clinical Experience with α-Particle–Emitting ²¹¹At: Treatment of Recurrent Brain Tumor Patients with ²¹¹At-Labeled Chimeric Antitenascin Monoclonal Antibody 81C6

Michael R. Zalutsky, David A. Reardon, Gamal Akabani et al. · Journal of Nuclear Medicine · 2007 · 396 citations · Full text

Medicine, Nuclear Medicine, Oncology +17

Labeling monoclonal antibodies and F(ab')2 fragments with the alpha-particle-emitting nuclide astatine-211: preservation of immunoreactivity and in vivo localizing capacity.

Michael R. Zalutsky, P K Garg, H. S. Friedman et al. · Proceedings of the National Academy of Sciences · 1989 · 153 citations · Full text

Medicine, Nuclear Medicine, Oncology +17

Reagents for Astatination of Biomolecules:  Comparison of the in Vivo Distribution and Stability of Some Radioiodinated/Astatinated Benzamidyl and<i>nido</i>-Carboranyl Compounds

D. Scott Wilbur, Ming‐Kuan Chyan, Donald K. Hamlin et al. · Bioconjugate Chemistry · 2003 · 114 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Astatination of proteins using an N-succinimidyl tri-n-butylstannyl benzoate intermediate

Michael R. Zalutsky, Acharan S. Narula · International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes · 1988 · 100 citations

Life Sciences, Biochemistry, Protein Biochemistry +3

Comparative tissue distribution in mice of the alpha-emitter 211At and 131I as labels of a monoclonal antibody and F(ab')2 fragment.

P K Garg, Cary L. Harrison, Michael R. Zalutsky · PubMed · 1990 · 83 citations

Medicine, Nuclear Medicine, Radiology +16