Pitfalls and limitations in using 4,5-diaminofluorescein for evaluating the influence of polyphenols on nitric oxide release from endothelial cells

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.8K citations

Veterinary Medicine, Cell Biology, Physiology +10

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

L J Ignarro, Georgette M. Buga, K S Wood et al. · Proceedings of the National Academy of Sciences · 1987 · 5.1K citations · Full text

Medicine, Pharmacology, Physiology +12

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

John Garthwaite, Sarah L. Charles, Russ Chess‐Williams · Nature · 1988 · 2.6K citations

Life Sciences, Neurobiology, Neuroscience +13

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

Michael A. Marletta, Poksyn S. Yoon, Radha Iyengar et al. · Biochemistry · 1988 · 1.6K citations

Life Sciences, Immunology, Microbiology +13

Permanent cell line expressing human factor VIII-related antigen established by hybridization.

C J Edgell, C. McDonald, John B. Graham · Proceedings of the National Academy of Sciences · 1983 · 1.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12