Pesticide Science · 1991 · 105 citations · 28 references
Antifungal AgentBioorganic ChemistryEngineeringBiochemistrySynthetic Agricultural FungicidesNatural β‐MethoxyacrylatesNatural SciencesMitochondrial RespirationNatural Product BiosynthesisOrganic ChemistryChemical BiologyPharmacologyPharmaceutical ChemistryBiomolecular EngineeringNatural Product Synthesis
Abstract The strobilurins and oudemansins are natural β‐methoxyacrylates which inhibit mitochondrial respiration and, as a result, have fungicidal activity. A knowledge of the structures (configuration and conformation) and properties of these compounds has allowed the preparation of analogues in which both fungicidal activity and stability have been improved.
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W.F. Becker, Gebhard von Jagow, Timm Anke et al. · FEBS Letters · 1981 · 259 citations
Molecular Pharmacology, Medicinal Chemistry, Respiratory Chain +14