Concepedia

Palladium‐Catalyzed CH Activation of<i>tert</i>‐Butyl Groups: A Simple Synthesis of 1,2‐Dihydrocyclobutabenzene Derivatives

Gerald Dyker

Angewandte Chemie International Edition in English · 1994 · 202 citations · 9 references

DOI

Concepts

Abstract

The tert-butyl group of 1 is surprisingly reactive in the presence of palladium catalysts. A domino coupling affords 1,2-dihydrocyclobutabenzene 2 in good yield (75%). The observed CH activation can also be used for cross coupling reactions.

References

9

Development of organopalladium(IV) chemistry: fundamental aspects and systems for studies of mechanism in organometallic chemistry and catalysis

Allan J. Canty · Accounts of Chemical Research · 1992 · 412 citations · Full text

, , +7

Ortho-alkylation of acetanilides using alkyl halides and palladium acetate

Samuel J. Tremont, Hayat Ur Rahman · Journal of the American Chemical Society · 1984 · 291 citations

, , +8

Palladium‐Catalyzed CH Activation of Methoxy Groups: A Facile Synthesis of Substituted 6<i>H</i>‐Dibenzo[<i>b</i>,<i>d</i>]pyrans

Gerald Dyker · Angewandte Chemie International Edition in English · 1992 · 240 citations

, , +10

Organometallic chemistry of electrophilic transition and lanthanide metal ions. The dominant pathways for reactions involving carbon-carbon double and single bonds and carbon-hydrogen bonds

Ayusman Sen · Accounts of Chemical Research · 1988 · 102 citations

, , +14

Transition metal catalyzed annulation reactions. Part 3. Palladium-catalyzed annulation reactions of 1,8-diiodonaphthalene

Gerald Dyker · The Journal of Organic Chemistry · 1993 · 94 citations

, , +13