Neonatology · 2010 · 15 citations · 2 references
PharmacyPharmacologyPharmacotherapyCardiovascular PharmacotherapyPediatric PharmacotherapyPediatric TherapeuticsPediatric Skin TumorsPediatric TumorsPediatric Soft Tissue TumorsPropranolol Therapy
Haemangiomas are the most common soft tissue tumours in infancy, occurring in approximately 5-10% of 1-year-old children. Current drug-based therapeutic options for large haemangiomas include corticosteroids, α-interferon and vincristin, all of which can result in harmful side effects. Recently, promising results have been reported using the non-cardio-selective β-blocker propranolol for the treatment of cutaneous capillary haemangiomas, in which a spectacular size reduction was observed during the first 7 days of treatment. We here report a similar significant and rapid inhibitory effect of propranolol on the growth of a viscerally located congenital haemangioma.
2
Gisela D’Angelo, Hsinyu Lee, Richard I. Weiner · Journal of Cellular Biochemistry · 1997 · 198 citations · Full text