C-type inactivation of a voltage-gated K+ channel occurs by a cooperative mechanism

Restoration of Inactivation in Mutants of <i>Shaker</i> Potassium Channels by a Peptide Derived from ShB

William N. Zagotta, Toshinori Hoshi, Richard W. Aldrich · Science · 1990 · 760 citations

Natural Sciences, Biochemistry, Molecular Biology +15

Two types of inactivation in Shaker K+ channels: Effects of alterations in the carboxy-terminal region

Toshinori Hoshi, William N. Zagotta, Richard W. Aldrich · Neuron · 1991 · 702 citations

Natural Sciences, Biochemistry, Biophysics +13

Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels.

José López‐Barneo, Toshinori Hoshi, Stefan H. Heinemann et al. · PubMed · 1993 · 597 citations

Natural Sciences, Biochemistry, Biophysics +15

The aromatic binding site for tetraethylammonium ion on potassium channels

Lise Heginbotham, Roderick MacKinnon · Neuron · 1992 · 452 citations

Natural Sciences, Biochemistry, Biophysics +16

Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels.

K L Choi, Richard W. Aldrich, Gary Yellen · Proceedings of the National Academy of Sciences · 1991 · 439 citations

Natural Sciences, Biophysics, Pharmacology +17