Frequent loss of heterozygosity in the β2-microglobulin region of chromosome 15 in primary human tumors

Human epithelial ovarian cancer allelotype.

William A. Cliby, S Ritland, Lynn C. Hartmann et al. · PubMed · 1993 · 242 citations

Life Sciences, Genetics, Oncology +11

HLA Class I Antigen Down-regulation in Primary Laryngeal Squamous Cell Carcinoma Lesions as a Poor Prognostic Marker

Takeshi Ogino, Hiroshi Shigyo, Hideyuki Ishii et al. · Cancer Research · 2006 · 190 citations · Full text

Medicine, Immunology, Oncology +16

Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β₂‐microglobulin inactivation in MSI‐positive tumors and LMP7/TAP2 downregulation in MSI‐negative tumors

Carmen Cabrera, P. Jiménez, Teresa Cabrera et al. · Tissue Antigens · 2003 · 157 citations

Life Sciences, Immunology, Oncology +17

Mutations of the β₂‐<i>microglobulin</i> gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides

Ricardo Benítez Benítez, D. Godelaine, Miguel Ángel López‐Nevot et al. · Tissue Antigens · 1998 · 147 citations

Life Sciences, Immunology, Oncology +17

Coordinated downregulation of the antigen presentation machinery and HLA class I/β2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer

José María Romero, Pilar Jiménez, Teresa Cabrera et al. · International Journal of Cancer · 2004 · 138 citations · Full text

Life Sciences, Immunology, Oncology +17