Hyperactivity of the hypothalamo‐pituitary‐adrenal axis in obesity: a study of ACTH, AVP, β‐lipotrophin and Cortisol responses to insulin‐induced hypoglycaemia

Abstract

Obesity is associated with increased activity of the hypothalamo-pituitary-adrenal axis as supported by augmented ACTH and beta-lipotrophin secretion in response to insulin-induced hypoglycaemia and the positive association between the ACTH response and the body weight of obese women studied.