napts, a Mutation affecting sodium channel activity in Drosophila, Is an allele of mle a regulator of X chromosome transcription

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Efficient<i>in vitro</i>synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

Douglas A. Melton, Paul A. Krieg, Michael R. Rebagliati et al. · Nucleic Acids Research · 1984 · 6.4K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +11

Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold.

John E. Walker, M Saraste, M J Runswick et al. · The EMBO Journal · 1982 · 5.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

The isolation of structural genes from libraries of eucaryotic DNA

Tom Maniatis, Ross C. Hardison, Elizabeth Lacy et al. · Cell · 1978 · 1.9K citations

Life Sciences, Genetics, Molecular Biology +11

Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing

Frank A. Laski, Donald C. Rio, Gerald M. Rubin · Cell · 1986 · 574 citations

Life Sciences, Genetics, Molecular Genetics +16