Antimicrobial peptide response to blood translocation of bacterial DNA in Crohnʼs disease is affected by NOD2/CARD15 genotype - Concepedia

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Publication | Open Access

Antimicrobial peptide response to blood translocation of bacterial DNA in Crohnʼs disease is affected by NOD2/CARD15 genotype

DOI Full Paper Access

50

Citations

37

References

2010

Year

Ana Gutiérrez, Ernst Holler, Pedro Zapater, Laura Sempere, Rodrigo Jover, Miguel Pérez‐Mateo, Juergen Schöelmerich, José M. Such, Reiner Wiest, Rubén Francés

Inflammatory Bowel Diseases

Abstract

β-Defensin 2, LL-37, and proinflammatory cytokines are increased in CD patients with bacterial-DNA in a concentration-dependent manner. NOD2/CARD15 plays a key role in the regulation of this response.

References

	Year	Citations

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