Colon perforation with acute peritonitis after taking clindamycin and diclofenac following wisdom tooth removal

The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.

Jianmin Fu, Jaime L. Masferrer, Karen Seibert et al. · Journal of Biological Chemistry · 1990 · 943 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Diaphragm disease: pathology of disease of the small intestine induced by non-steroidal anti-inflammatory drugs.

J Láng, Ashley B. Price, A J Levi et al. · Journal of Clinical Pathology · 1988 · 361 citations · Full text

Medicine, Pharmacotherapy, Bowel Management +12

Comparison of rofecoxib and celecoxib, two cyclooxygenase-2 inhibitors, in postoperative dental pain: A randomized, placebo- and active-comparator-controlled clinical trial

Kerstin Malmström, Stephen Daniels, Paul Kotey et al. · Clinical Therapeutics · 1999 · 261 citations

Medicine, Maxillofacial Surgery, Orofacial Pain +14

Diclofenac acyl glucuronide, a major biliary metabolite, is directly involved in small intestinal injury in rats

Sven Seitz, Urs A. Boelsterli · Gastroenterology · 1998 · 118 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

Incidence of gastroduodenal ulcers associated with valdecoxib compared with that of ibuprofen and diclofenac in patients with osteoarthritis

David Sikes, Naurang M. Agrawal, William W. Zhao et al. · European Journal of Gastroenterology & Hepatology · 2002 · 105 citations

Medicine, Pharmacology, Pharmacotherapy +16