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<i>Gnathotrichus sulcatus</i> : Synergistic Response to Enantiomers of the Aggregation Pheromone Sulcatol
149
Citations
10
References
1976
Year
EntomologyField BioassaysAggregation Pheromone SulcatolSynergistic ResponseGnathotrichus SulcatusPheromone BiochemistryBiochemistryG Protein-coupled ReceptorReceptor (Biochemistry)Mechanism Of ActionSemiochemicalPharmacologyBiologyFunctional SelectivityNatural SciencesIsomeric RatioMedicineBiotic InteractionDrug DiscoveryNeuropeptides
In laboratory and field bioassays, Gnathotrichus sulcatus responded to sulcatol (6-methyl-5-hepten-2-ol) only when both enantiomers were present. Response was greater to racemic sulcatol than to a mixture (65 : 35) of S-(+) and R-(-) enantiomers, the naturally occurring isomeric ratio. Enantiomer-specific active sites on receptor proteins in the same or different cells are implicated.
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