Symmetrical and Asymmetrical Bisphosphonate Esters. Synthesis, Selective Hydrolysis, and Isomerization

Bisphosphonates act on rat bone resorption through the mediation of osteoblasts.

Mohan Singh Sahni, Harald L. Guenther, H. Fleisch et al. · Journal of Clinical Investigation · 1993 · 415 citations · Full text

Medicine, Chemical Biology, Bone Augmentation +16

BM 21.0955, a potent new bisphosphonate to inhibit bone resorption

R. C. Mühlbauer, Frieder Bauss, Robert Schenk et al. · Journal of Bone and Mineral Research · 1991 · 243 citations

Medicine, Medicinal Chemistry, Bone Metabolism +10

Studies in the triazine series including a new synthesis of 1:2:4-triazines

Perttu V. Laakso, R. A. Robinson, H.P. Vandrewala · Tetrahedron · 1957 · 96 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

278. The reaction between trialkyl phosphites and alkyl halides

A. H. Ford‐Moore, J. Howarth Williams · Journal of the Chemical Society (Resumed) · 1947 · 90 citations

Natural Sciences, Chemistry, Organic Chemistry +2

Anion-exchange separation and determination of bisphosphonates and related analytes by post-column indirect fluorescence detection

Michael Lovdahl, Donald J. Pietrzyk · Journal of Chromatography A · 1999 · 65 citations

Natural Sciences, Chemistry, Pharmaceutical Analysis +10