Concepedia

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS

Vaibhav B. Patel, Nicola E. Clarke, Zuocheng Wang, Fan Dong, Nirmal Parajuli, Ratnadeep Basu, Brendan Putko, Zamaneh Kassiri, Anthony J. Turner, Gavin Y. Oudit

Journal of Molecular and Cellular Cardiology · 2013 · 333 citations · 32 references

DOIFull text

Open access

Concepts

References

32

A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9

Mary Donoghue, F. Hsieh, Elizabeth Baronas et al. · Circulation Research · 2000 · 3.1K citations · Full text

, , +11

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature · 1997 · 3.1K citations

, , +14

A Human Homolog of Angiotensin-converting Enzyme

Sarah R. Tipnis, Nigel M. Hooper, Ralph Hyde et al. · Journal of Biological Chemistry · 2000 · 2K citations · Full text

, , +12

Angiotensin-converting enzyme 2 is an essential regulator of heart function

Michael A. Crackower, Renu Sarao, Gavin Y. Oudit et al. · Nature · 2002 · 1.8K citations

, , +10

Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2

Carlos M. Ferrario, Jewell A. Jessup, Mark C. Chappell et al. · Circulation · 2005 · 1.6K citations

, , +14