Octahydro-1,2,3,4,4a,5,11,11a-pyrido[3,4-c][1,5]benzoxazepines: conformationally restricted fentanyl analogs

Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

Michael J. S. Dewar, Eve G. Zoebisch, Eamonn F. Healy et al. · Journal of the American Chemical Society · 1985 · 13.1K citations

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Systematic analysis of structural data as a research technique in organic chemistry

Frank H. Allen, Olga Kennard, Robin Taylor · Accounts of Chemical Research · 1983 · 1K citations

Natural Sciences, Chemistry, Analytical Chemistry +12

Synthesis of some conformationally restricted analogs of fentanyl

Joel G. Berger, Fredric Davidson, Gordon E. Langford · Journal of Medicinal Chemistry · 1977 · 39 citations

Pharmacy, Chemistry, Pharmacology +9

4-Phenyl- and 4-heteroaryl-4-anilidopiperidines. A novel class of analgesic and anesthetic agents

Linas V. Kudzma, Sherry A. Severnak, Mark J. Benvenga et al. · Journal of Medicinal Chemistry · 1989 · 39 citations

Medicine, Medicinal Chemistry, Pharmacology +17

4-Anilidopiperidine analgesics. 2. A study of the conformational aspects of the analgesic activity of the 4-anilidopiperidines utilizing isomeric N-substituted 3-(propananilido)nortropane analogs

Thomas N. Riley, Jerome R. Bagley · Journal of Medicinal Chemistry · 1979 · 38 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14