Simple, Extremely Fast, and High‐Yielding Oxidation of Thiols to Disulfides

Abstract

Abstract Results of oxidation of thiols to disulfides with 1,3‐dibromo‐5,5‐dimethylhydantoin (DBDMH) are described. A simple addition of 0.20–0.25 mol equivalent of solid DBDMH to thiol in chloroform at room temperature yielded the disulfides in excellent yield. The reaction is extremely fast and gave no other oxidized side products. Keywords: 1,3‐Dibromo‐5,5‐dimethylhydantoindisulfidesoxidation of thiols Additional informationNotes on contributorsAshraful Alam On leave from Department of Chemistry, Shahjalal University of Science and Technology, Sylhet-3114, Bangladesh.