Concepedia

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

Vigo Heissmeyer, Fernando Macián, Sin‐Hyeog Im, Rajat Varma, Stefan Feske, K. Venuprasad, Hua Gu, Yun‐Cai Liu, Michael L. Dustin, Anjana Rao

Nature Immunology · 2004 · 512 citations · 43 references

DOI

Concepts

References

43

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

, , +17

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

Arash Grakoui, Shannon K. Bromley, Cenk Sumen et al. · Science · 1999 · 3.1K citations

, , +16

Three-dimensional segregation of supramolecular activation clusters in T cells

Colin R. F. Monks, Benjamin A. Freiberg, Hannah Kupfer et al. · Nature · 1998 · 2.3K citations

, , +16

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

Michael L. Dustin, Timothy A. Springer · Nature · 1989 · 1.5K citations

, , +12

Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I

David J. Katzmann, Markus Babst, Scott D. Emr · Cell · 2001 · 1.4K citations · Full text

, , +14