Continuous changes in the optical properties of liver tissue during laser‐induced interstitial thermotherapy

Abstract

The optical properties of liver tissue change significantly under the influence of tissue heating, resulting in a decreased optical penetration depth. These changes occur mainly in the temperature range of 50 degrees C to 65 degrees C, corresponding to protein denaturation. To ensure a safe and effective procedure, an adjustment of the laser power to the actual penetration depth is recommended during therapy.