Concepedia

FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer

Tonia L. Vincent, Celia McLean, Louise E. Full, David Peston, Jeremy Saklatvala

Osteoarthritis and Cartilage · 2007 · 220 citations · 40 references

DOI

Concepts

References

40

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Avner Yayon, Michael Klagsbrun, Jeffrey D. Esko et al. · Cell · 1991 · 2.4K citations

, , +15

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

Keith Burridge, Christopher E. Turner, Lewis H. Romer · The Journal of Cell Biology · 1992 · 1.3K citations · Full text

, , +17

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.

Shingo Miyamoto, Hidemi Teramoto, Omar A. Coso et al. · The Journal of Cell Biology · 1995 · 1.2K citations · Full text

, , +17

Integrin-mediated cell adhesion activates mitogen-activated protein kinases.

Qing Chen, Michael S. Kinch, Taichen Lin et al. · Journal of Biological Chemistry · 1994 · 656 citations · Full text

, , +15

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

David Aviezer, Dalit Hecht, Michal Safran et al. · Cell · 1994 · 535 citations

, , +9