Concepedia

Structure and chromosome mapping of the human SIX4 and murine <i>Six4</i> genes

Haruka Ozaki, Kaori Yamada, Makoto Kobayashi, Shuichi Asakawa, Satoshi Minoshima, N Shimizu, M. Kajitani, Kyoshi Kawakami

Cytogenetic and Genome Research · 1999 · 14 citations · 16 references

DOI

Concepts

Abstract

Six4, a member of the homeobox gene subfamily (Six), is expressed in a developmentally regulated fashion, and supposed to be involved in embryogenesis. We cloned the human SIX4 and murine Six4 genomic DNAs and determined their structures. The structure, including the 5' upstream region of both genes, was well conserved suggesting the conserved function and regulation of these genes. Human SIX4 was mapped to chromosome 14q23.

References

16

<i>Six3</i>, a murine homologue of the <i>sine oculis</i> gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development

Guillermo Oliver, Alvaro Mailhos, Roland Wehr et al. · Development · 1995 · 671 citations

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The drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system

Benjamin Cheyette, Patricia J. Green, K. Martin et al. · Neuron · 1994 · 513 citations

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The gene for arrhythmogenic right ventricular cardiomyopathy maps to chromosome 14q23–q24

Alessandra Rampazzo, Andrea Nava, Gian Antonio Danieli et al. · Human Molecular Genetics · 1994 · 337 citations

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Homeobox genes and connective tissue patterning

Guillermo Oliver, Roland Wehr, Nancy A. Jenkins et al. · Development · 1995 · 327 citations · Full text

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R-banding and nonisotopic in situ hybridization: precise localization of the human type II collagen gene (COL2A1)

Eiichi Takahashi, Tada-aki Hori, P. O’Connell et al. · Human Genetics · 1990 · 233 citations

, , +5