Disease Course in Patients with Autosomal Recessive Retinitis Pigmentosa due to the<i>USH2A</i>Gene

Abstract

On average, USH2A patients lose visual acuity faster than RHO patients and slower than RPGR patients. USH2A patients lose visual field and cone electroretinogram amplitude faster than patients with RHO or RPGR mutations. Patients with a nonsyndromic USH2A mutation have the same retinal disease course as patients with syndromic USH2A disease.