Concepedia

Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2)

Sheo B. Singh, David E. Kaelin, Jin Wu, Lynn Miesel, Christopher M. Tan, Todd A. Black, Ravi P. Nargund, Peter T. Meinke, David B. Olsen, Armando Lagrutta,

Bioorganic & Medicinal Chemistry Letters · 2015 · 41 citations · 15 references

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15

Invasive Methicillin-Resistant <EMPH TYPE="ITAL">Staphylococcus aureus</EMPH> Infections in the United States

R. Monina Klevens · JAMA · 2007 · 3.7K citations

, , +16

Type IIA topoisomerase inhibition by a new class of antibacterial agents

B.D. Bax, Pan F. Chan, Drake S. Eggleston et al. · Nature · 2010 · 842 citations

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Prevalence of Antimicrobial-Resistant Pathogens in Canadian Hospitals: Results of the Canadian Ward Surveillance Study (CANWARD 2008)

George G. Zhanel, Melanie DeCorby, Heather J. Adam et al. · Antimicrobial Agents and Chemotherapy · 2010 · 170 citations · Full text

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Mechanism of Action of the Antibiotic NXL101, a Novel Nonfluoroquinolone Inhibitor of Bacterial Type II Topoisomerases

Michael T. Black, Therese‐Marie Stachyra, Denis Platel et al. · Antimicrobial Agents and Chemotherapy · 2008 · 144 citations · Full text

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Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity

Folkert Reck, Richard A. Alm, Patrick Brassil et al. · Journal of Medicinal Chemistry · 2011 · 103 citations · Full text

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