Shape Analysis of the Peripapillary RPE Layer in Papilledema and Ischemic Optic Neuropathy

Abstract

The shape difference in papilledema, absent in AION, cannot be explained by disc edema alone. The difference is a consequence of both the translaminar pressure gradient and the material properties of the peripapillary sclera. GM offers a novel way of statistically assessing shape differences of the peripapillary optic nerve head.