Superficial Dermal Injection of Hyaluronic Acid Soft Tissue Fillers: Comparative Ultrasound Study

Abstract

Superficial placement of HAs is possible, as demonstrated by ultrasonography. Gels that do not have lidocaine within them are more painful. Injection of biphasic HA gels superficially in the dermis is associated with clinical erythema and tenderness and histology showing an eosinophilic infiltrate.