Plasma and albumin‐free recombinant factor VIII: pharmacokinetics, efficacy and safety in previously treated pediatric patients

Prophylaxis versus Episodic Treatment to Prevent Joint Disease in Boys with Severe Hemophilia

Marilyn J. Manco‐Johnson, Thomas C. Abshire, Amy D. Shapiro et al. · New England Journal of Medicine · 2007 · 1.9K citations · Full text

Medicine, Hematology, Orthopedic Surgery +13

Twenty‐five years' experience of prophylactic treatment in severe haemophilia A and B

I. M. Nilsson, Erik Berntorp, Thomas Löfqvist et al. · Journal of Internal Medicine · 1992 · 968 citations

Medicine, Hematology, Pediatrics +10

The Nijmegen Modification of the Bethesda Assay for Factor VIII:C Inhibitors: Improved Specificity and Reliability

Bert Verbruggen, I.R.O. Nováková, H. Wessels et al. · Thrombosis and Haemostasis · 1995 · 655 citations

Medicine, Hematology, Clinical Biochemistry +13

A longitudinal study of orthopaedic outcomes for severe factor‐VIII‐deficient haemophiliacs

Louis M. Aledort, R. H. HASCHMEYER, H. Pettersson · Journal of Internal Medicine · 1994 · 613 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +15

Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized

Jan Astermark, Pia Petrini, Lilian Tengborn et al. · British Journal of Haematology · 1999 · 280 citations · Full text

Medicine, Hematology, Pediatrics +13