British Journal of Dermatology · 1970 · 37 citations · 4 references
MedicineDermatologyPathologyDermatopathologyHistologyHistopathologyDermatopathology Of InfectionGranulomatous DermatosesImmunopathology Of SkinInfectious DermatosesInflammatory DermatosesSkin InfectionsDermatologic HistopathologyDermatological InfectionsDermatopathologic Lesion DescriptionHistopathology Of Skin LesionsHistopathology Of The SkinHistoplasmosis LesionsMicroscopic Tissue ExaminationParasitic Skin Infection
SUMMARY.— Involvement of the skin is a frequent feature of African histoplasmosis. The skin lesions may represent the sole manifestation of the disease or they may be part of widely disseminated involvement of various organs. Three main types of skin lesions are encountered: (a) Superficial cutaneous granuloma, (b) Subcutaneous granuloma and abscess, (c) Osteomyelitic lesions with secondary involvement of the skin. The characteristic features of the skin lesions, and the differential diagnosis from other dermatological conditions are described. The diagnosis can be made on clinical examination of a typical case and it can be confirmed by microscopic examination of the exudate, by histological examination of the biopsy material, and by culture of the organism.
4