Cardiovascular effects induced by <i>Cymbopogon winterianus</i> essential oil in rats: involvement of calcium channels and vagal pathway

Abstract

These results demonstrated that EOCW induced hypotension and vasorelaxation. These effects appeared to be mainly mediated by Ca(+2)-channel blocking. Furthermore, the higher dose of EOCW induced transient bradycardia and arrhythmias due to a cardiac muscarinic activation secondary to a vagal discharge.