Effects of amifostine on perfused isolated rat heart and on acute doxorubicin-induced cardiotoxicity

Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer.

Graham J. Kemp, Peter S. Rose, John R. Lurain et al. · Journal of Clinical Oncology · 1996 · 467 citations

Uptake of WR-2721 derivatives by cells in culture: identification of the transported form of the drug.

Paula M. Calabro-Jones, José Aguilera, John F. Ward et al. · PubMed · 1988 · 143 citations

Pharmaceutical Science, Bioorganic Chemistry, Cellular Pharmacology +19

Adriamycin-induced myocardial dysfunction in vitro is mediated by free radicals

Vivian K Lee, A. K. Randhawa, Pawan K. Singal · American Journal of Physiology-Heart and Circulatory Physiology · 1991 · 111 citations

Cardiac Muscle, Heart Failure, Lipid Peroxidation +18

Pharmacokinetics of amifostine and its metabolites in patients

A.E.C. Korst, Corien Eeltink, Jan B. Vermorken et al. · European Journal of Cancer · 1997 · 50 citations

Pharmacological Study, Medicine, Pharmacotherapy +2

Acute Doxorubicin Cardiotoxicity

P. Pelikán, Myron L. Weisfeldt, William E. Jacobus et al. · Journal of Cardiovascular Pharmacology · 1986 · 49 citations

Hypertension, Cardiovascular Disease, Doxorubicin-exposed Hearts +10