Concepedia

Effect of Hydroxymethyl Glutaryl Coenzyme A Reductase Inhibitor Therapy on High Sensitive C-Reactive Protein Levels

Ishwarlal Jialal, Daniel T. Stein, David S. Balis, Scott M. Grundy, Beverley Adams‐Huet, Sridevi Devaraj

Circulation · 2001 · 731 citations · 16 references

Open access

Abstract

Pravastatin, simvastatin, and atorvastatin significantly decreased levels of hs-CRP. These data support an anti-inflammatory effect of these drugs.

References

16

C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women

Paul M. Ridker, Charles H. Hennekens, Julie E. Buring et al. · New England Journal of Medicine · 2000 · 5.8K citations · Full text

Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men

Paul M. Ridker, Mary Cushman, Meir J. Stampfer et al. · New England Journal of Medicine · 1997 · 5.5K citations · Full text

Direct Proinflammatory Effect of C-Reactive Protein on Human Endothelial Cells

Vincenzo Pasceri, James T. Willerson, Edward T.H. Yeh · Circulation · 2000 · 1.9K citations · Full text

Long-Term Effects of Pravastatin on Plasma Concentration of C-reactive Protein

Paul M. Ridker, Nader Rifai, Marc A. Pfeffer et al. · Circulation · 1999 · 1.5K citations · Full text

Inflammation, Pravastatin, and the Risk of Coronary Events After Myocardial Infarction in Patients With Average Cholesterol Levels

Paul M. Ridker, Nader Rifai, Marc A. Pfeffer et al. · Circulation · 1998 · 1.4K citations