Pediatric Neurosurgery · 1989 · 23 citations · 0 references
Immunohistochemical StudiesBrain DevelopmentNeurotransmitterHuman FetusesCellular NeurobiologyEmbryologyNeuroendocrine MechanismNeurochemistryReticular FormationsHealth SciencesCentral Superior NucleiFetal NeurodevelopmentNervous SystemCell BiologyDevelopmental BiologyNeurophysiologyNeuroanatomyPhysiology5-Ht-positive NeuronsNeuroscienceCentral Nervous SystemMedicinePositive 5-Ht Cells
5-HT-positive neurons were detected by the PAP immunohistochemical methods in different nuclei of the reticular formations of human fetuses as early as 10 weeks of gestation. The majority of positive 5-HT cells were located in dorsal raphe and central superior nuclei, and there was a reduction of these neurons per 40-microns section as the fetus aged.