Survey of Anesthesiology · 1982 · 31 citations · 0 references
MedicineAnesthesiologySurgeryAnesthesiaCardiothoracic AnesthesiologyCardiothoracic SurgeryCardiovascular Effects Of AnesthesiaCoronary Artery Bypass Grafting AnesthesiaHemodynamic Response To AnesthesiaIntraoperative Hemodynamic ManagementPerioperative Hemodynamic ManagementHeart RateHemodynamic Effects Of AnesthesiaHemodynamic Effects Of AnestheticsHemodynamic Response To Surgical StimuliLaryngoscopy AnesthesiaPerioperative Hemodynamic ControlRate-pressure ProductSystolic Blood Pressure
The use of propranolol to control heart rate (HR), systolic pressure, and rate-pressure product (RPP) during laryngoscopy and sternotomy was studied in 21 patients, New York Heart Association functional Classes 1 and 2, scheduled for coronary artery bypass graft surgery. All patients were anesthetized in an identical fashion, but the treatment group (N = 13) received propranolol, 0.5 to 1 mg IV, 4 minutes before laryngoscopy and again, in most cases, before skin incision. Patients not given propranolol (N = 8) showed a clinically and statistically significant increase in HR and RPP, whereas HR and RPP remained essentially unchanged from the preanesthetic period in patients given propranolol.