Antimycotic sterol biosynthesis inhibitors

Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes.

David S. Loose, Patricia B. Kan, M Hirst et al. · Journal of Clinical Investigation · 1983 · 446 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17

Inhibition of Human Estrogen Synthetase (Aromatase) by Flavones

James T. Kellis, Larry E. Vickery · Science · 1984 · 310 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Biochemical effects of miconazole on fungi. II. Inhibition of ergosterol biosynthesis in Candida albicans

H. Van den Bossche, G. Willemsens, W Cools et al. · Chemico-Biological Interactions · 1978 · 289 citations

Life Sciences, Biochemistry, Microbiology +16

Comparison of the in Vitro Antifungal Activities of Miconazole and a New Imidazole, R41,400

Dennis R. Dixon, Smith Shadomy, H. Jean Shadomy et al. · The Journal of Infectious Diseases · 1978 · 147 citations

Life Sciences, Infectious Diseases, Microbiology +17

Ketoconazole, an oral antifungal: laboratory and clinical assessment of imidazole drugs

Dante Borelli, José L. Bran, J. Fuentes et al. · Postgraduate Medical Journal · 1979 · 147 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16